Genome sequencing

The genome of an organism is the collection of genes that are organized in chromosomes and that contain the genetic material necessary for its development, growth and maintenance. The genome sequence therefore contains information on all the genes present in the genome, namely their DNA sequence and location in the genome. The IPHC has set out to generate a first draft of the genome of the Pacific halibut. The sequencing of the Pacific halibut genome will allow the identification of genomic regions and genes that are responsible for temporal and spatial adaptive and phenotypic characteristics and better understand genetic and evolutionary changes that occur in response to environmental and fisheries-related influences. Therefore, the genome sequence will be essential for understanding possible changes in the genetic constitution of the Pacific halibut population. Importantly, the genome sequence will also assist in understanding the genetic basis of growth, reproductive performance, migratory behavior, etc. in this species. In the short term, the genome sequence will allow IPHC to effectively map and capitalize information derived from all the identified SNPs associated with sex that are being derived through RAD sequencing as well as the transcripts generated from our current RNA sequencing efforts. Ultimately, the genome sequence of the Pacific halibut will provide the means to link genotype and phenotype in this species.